Discovering functions for the actin cytoskeleton in health, aging, and disease

Our research goals are to determine (1) how the cytoskeleton controls the organization, shape, and movement of cells and their internal components; (2) how cytoskeletal remodeling is altered by infectious microbes and genetic mutations; and (3) how cytoskeletal functions affect biological aging.  We use a combination of bioinformatic, genetic, biochemical, molecular, cellular, and organismal approaches to study these processes.